Dr Markus Kuhn published in 1999 an article [1] explaining in details
why we shouldn't use the ASCII grave accent (0x60) as a left quotation.

Backticks have been used most notably to produce nice-looking LaTeX
documents but it doesn't seem to be an issue on modern platforms and
for the oldest ones, there are workarounds as mentioned by Dr Kuhn.

[1]: https://www.cl.cam.ac.uk/~mgk25/ucs/quotes.html